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liver carcinoma hepg 2  (ATCC)


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    Structured Review

    ATCC liver carcinoma hepg 2
    Antiproliferative, and anti-Topoisomerase I and II activities of the purified AME of A. alternata. A , The anti-proliferative activity of the purified AME towards the different cell lines <t>(MCF7,</t> <t>HepG-2</t> cells,Caco2, and normal OEC cells), compared to Taxol as a positive control. Kinetics of Topoisomerase I ( B ) and Topoisomerase II ( C ), inhibition at different concentrations of AME by A. alternata as shown from agarose gel (upper panel), and IC50 value (lower panel).
    Liver Carcinoma Hepg 2, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 29964 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/liver+carcinoma+hepg+2/Hep+G2/pmc13184112-45-10-13
    Average 99 stars, based on 29964 article reviews
    liver carcinoma hepg 2 - by Bioz Stars, 2026-10
    99/100 stars

    Images

    1) Product Images from "Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations"

    Article Title: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations

    Journal: Scientific Reports

    doi: 10.1038/s41598-026-51757-8

    Antiproliferative, and anti-Topoisomerase I and II activities of the purified AME of A. alternata. A , The anti-proliferative activity of the purified AME towards the different cell lines (MCF7, HepG-2 cells,Caco2, and normal OEC cells), compared to Taxol as a positive control. Kinetics of Topoisomerase I ( B ) and Topoisomerase II ( C ), inhibition at different concentrations of AME by A. alternata as shown from agarose gel (upper panel), and IC50 value (lower panel).
    Figure Legend Snippet: Antiproliferative, and anti-Topoisomerase I and II activities of the purified AME of A. alternata. A , The anti-proliferative activity of the purified AME towards the different cell lines (MCF7, HepG-2 cells,Caco2, and normal OEC cells), compared to Taxol as a positive control. Kinetics of Topoisomerase I ( B ) and Topoisomerase II ( C ), inhibition at different concentrations of AME by A. alternata as shown from agarose gel (upper panel), and IC50 value (lower panel).

    Techniques Used: Purification, Activity Assay, Positive Control, Inhibition, Agarose Gel Electrophoresis

    Related Articles

    Activity Assay:

    Article Title: Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
    Article Snippet: .. The activity of constructed Glutathione-Epothilone B conjugate against the liver carcinoma (HepG-2) (ATCC HB-8065), and normal epithelial cells (THLE-2) (ATCC CRL-2706) was determined by the MTT reagent [ ]. ..

    Article Title: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations
    Article Snippet: .. The antiproliferative activity of purified AME was evaluated towards the liver carcinoma (HepG-2) (ATCC, HB-8065), breast carcinoma (MCF7) (ATCC, HTB-22), human colorectal carcinoma cell line (Caco-2) (ATCC, HTB-37), in addition to the Oral Epithelial Cells (OEC) by the MTT reagent . .. The cells were cultured on DMEM medium (Invitrogen, Life Technol.) of 10% FBS, and 10 μg/ml insulin.

    Construct:

    Article Title: Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
    Article Snippet: .. The activity of constructed Glutathione-Epothilone B conjugate against the liver carcinoma (HepG-2) (ATCC HB-8065), and normal epithelial cells (THLE-2) (ATCC CRL-2706) was determined by the MTT reagent [ ]. ..

    MTT Assay:

    Article Title: Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
    Article Snippet: .. The activity of constructed Glutathione-Epothilone B conjugate against the liver carcinoma (HepG-2) (ATCC HB-8065), and normal epithelial cells (THLE-2) (ATCC CRL-2706) was determined by the MTT reagent [ ]. ..

    Article Title: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations
    Article Snippet: .. The antiproliferative activity of purified AME was evaluated towards the liver carcinoma (HepG-2) (ATCC, HB-8065), breast carcinoma (MCF7) (ATCC, HTB-22), human colorectal carcinoma cell line (Caco-2) (ATCC, HTB-37), in addition to the Oral Epithelial Cells (OEC) by the MTT reagent . .. The cells were cultured on DMEM medium (Invitrogen, Life Technol.) of 10% FBS, and 10 μg/ml insulin.

    Purification:

    Article Title: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations
    Article Snippet: .. The antiproliferative activity of purified AME was evaluated towards the liver carcinoma (HepG-2) (ATCC, HB-8065), breast carcinoma (MCF7) (ATCC, HTB-22), human colorectal carcinoma cell line (Caco-2) (ATCC, HTB-37), in addition to the Oral Epithelial Cells (OEC) by the MTT reagent . .. The cells were cultured on DMEM medium (Invitrogen, Life Technol.) of 10% FBS, and 10 μg/ml insulin.



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    Image Search Results


    Antiproliferative, and anti-Topoisomerase I and II activities of the purified AME of A. alternata. A , The anti-proliferative activity of the purified AME towards the different cell lines (MCF7, HepG-2 cells,Caco2, and normal OEC cells), compared to Taxol as a positive control. Kinetics of Topoisomerase I ( B ) and Topoisomerase II ( C ), inhibition at different concentrations of AME by A. alternata as shown from agarose gel (upper panel), and IC50 value (lower panel).

    Journal: Scientific Reports

    Article Title: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations

    doi: 10.1038/s41598-026-51757-8

    Figure Lengend Snippet: Antiproliferative, and anti-Topoisomerase I and II activities of the purified AME of A. alternata. A , The anti-proliferative activity of the purified AME towards the different cell lines (MCF7, HepG-2 cells,Caco2, and normal OEC cells), compared to Taxol as a positive control. Kinetics of Topoisomerase I ( B ) and Topoisomerase II ( C ), inhibition at different concentrations of AME by A. alternata as shown from agarose gel (upper panel), and IC50 value (lower panel).

    Article Snippet: The antiproliferative activity of purified AME was evaluated towards the liver carcinoma (HepG-2) (ATCC, HB-8065), breast carcinoma (MCF7) (ATCC, HTB-22), human colorectal carcinoma cell line (Caco-2) (ATCC, HTB-37), in addition to the Oral Epithelial Cells (OEC) by the MTT reagent .

    Techniques: Purification, Activity Assay, Positive Control, Inhibition, Agarose Gel Electrophoresis